Any lesion to the human body that damages a blood vessel causes platelets to be activated at the site of the lesion. These cells, which have no nucleus, gather together to create a ‘plug’ to stop blood loss. The platelets then break open, releasing the growth factors they contain, so in addition to the normal process of coagulation there is a subsequent process of tissue repair. The platelets’ growth factor content is fundamental to the repair process, as these growth factors stimulate migration, growth, multiplication and differentiation of the cells that repair the tissue. Production and remodelling of new collagen is stimulated in this way. Plasma that is rich in platelets and therefore growth factors can be obtained by simply drawing blood and centrifuging it. These growth factors can be injected using very small thin needles, stimulating new collagen production, and this mechanism can be activated exactly where it is needed. The resulting rejuvenation of the treated area (face, backs of hands, decolletage, arms) is very evident. The same treatment has proved very effective in improving hair growth and in reducing healing time after ablative laser resurfacing.
PRGF (Plasma rich in growth factors)
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